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Transplantation d’un patch bioimprimé 3D dans un modèle murine d’infarctus du myocarde
JoVE 신문
생체공학
Author Produced
This content is Free Access.
JoVE 신문 생체공학
Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction
DOI:

07:47 min

September 26, 2020

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Chapters

  • 00:00Introduction
  • 00:42Surgical Procedure
  • 01:18Preparing the Surgical Field
  • 01:31Left Lateral Thoracotomy
  • 02:00Left Anterior Descending (LAD) Permanent Coronary Artery Ligation
  • 02:583D Bioprinting and Culturing Patches (7-14 days before transplantation)
  • 04:19Transplantation of the Bioprinted Patch onto the Epicardium
  • 05:39Mouse Recovery
  • 06:29Representative Results
  • 06:45Conclusion

Summary

자동 번역

Ce protocole vise à transplanter un patch bioimprimé 3D sur l’épicardium de souris infarctus modélisant l’insuffisance cardiaque. Il comprend des détails concernant l’anesthésie, l’ouverture chirurgicale de coffre, la ligature permanente de l’artère coronaire antérieure descendante gauche (LAD) et l’application d’un patch bioimprimé sur la zone infarctus du coeur.

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