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1Department of Anesthesiology and Perioperative Medicine,Mayo Clinic, 2Division of Anesthesiology and Critical Care, Soroka University Medical Center and the Faculty of Health Sciences,Ben-Gurion University of the Negev, 3Department of Biophysics and Biochemistry,Oles Honchar Dnipro National University, 4Department of Neurosurgery, Soroka University Medical Center and the Faculty of Health Sciences,Ben-Gurion University of the Negev
Chapters
- 00:00Introduction
- 00:43Preparing Rats for the Experimental Procedure
- 02:14Induction of Depression in Rats
- 03:16Anti-depression Therapy
- 03:58The Social Organization Test (Complex Diving-for-Food Task)
- 05:19Performing Diving-for-Food Task
- 06:03Assessment of Depressive-like Behavior: The Sucrose Preference Test
- 07:14Representative Results
This protocol describes a method of examining social hierarchy in a rat model. Rats perform a complex diving-for-food task in which they form a distinct hierarchy according to their willingness to dive underwater and swim to obtain a food pellet. This method is used to understand decision making and social relationships among highly social animals in small groups.
