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1Department of Mechanical Engineering,Pohang University of Science and Technology (POSTECH), 2Department of Creative IT Engineering,Pohang University of Science and Technology (POSTECH), 3Department of Rural and Biosystems Engineering, College of Agriculture and Life Sciences,Chonnam National University
Chapters
- 00:05Introduction
- 00:56Collagen Pre-Gel Solution Preparation
- 01:471% Neutralized Collagen Pre-Gel Solution pH Adjustment
- 03:12Gas-Permeable Barrier 3D Printing
- 04:20Polydimethylsiloxane (PDMS) Barrier Casting
- 05:291% Neutralized Collagen Pre-Gel Solution Cell Mixing
- 06:19Cancer-Stroma Concentric Ring 3D Cell Printing
- 07:39Hypoxic Cancer-on-a-Chip Maintenance
- 08:11Results: Representative Solid Pathologic Cancer Progression on a 3D Cell-Printed Hypoxic Cancer-on-a-Chip
- 10:06Conclusion
Hypoxie ist ein Kennzeichen der Tumormikroumgebung und spielt eine entscheidende Rolle beim Fortschreiten des Krebses. Dieser Artikel beschreibt den Herstellungsprozess eines hypoxischen Krebs-auf-einem-Chip basierend auf der 3D-Zelldrucktechnologie, um eine hypoxiebedingte Pathologie von Krebs zu rekapitulieren.
