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Chapters
- 00:00Introduction
- 01:24Dorsal Full Thickness Excision Surgery
- 03:25In vivo Treatment and Assessment of Dispersal
- 07:04Ex vivo Assessment of Dispersal
- 09:12Results: Enzymatic Dispersal Leads to Bacterial Dissemination in the Host
- 10:55Conclusion
Here, we describe ex vivo and in vivo methods for assessing bacterial dispersal from a wound infection in mice. This protocol can be utilized to test the efficacy of topical antimicrobial and anti-biofilm therapies, or to assess the dispersal capacity of different bacterial strains or species.
