Journal
/
/
Generación de organoides pulmonares enteros en 3D a partir de células madre pluripotentes inducidas para modelar la biología y la enfermedad del desarrollo pulmonar
JoVE 신문
발생학
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 발생학
Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease
DOI:

09:45 min

April 12, 2021

, , ,

Chapters

  • 00:04Introduction
  • 01:05Definitive Endoderm Induction from Induced Pluripotent Stem Cells (Day 1-3)
  • 03:13Anterior Foregut Endoderm (AFE) Induction and Lung Progenitor Cell (LPC) Differentiation
  • 05:003D lung Organoid Induction (Day 16 22)
  • 06:493D Lung Organoid Branching and Maturation
  • 07:11Results: Characterization of Endoderm and 3D Whole Lung Organoids
  • 09:04Conclusion

Summary

자동 번역

El artículo describe la diferenciación dirigida paso a paso de células madre pluripotentes inducidas a organoides pulmonares enteros tridimensionales que contienen células pulmonares epiteliales proximales y distales junto con mesénquima.

Related Videos

Read Article