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うつ病の動物モデル - 慢性絶望モデル(CDM)
 
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うつ病の動物モデル - 慢性絶望モデル(CDM)

Article DOI: 10.3791/62579-v • 05:47 min • September 23rd, 2021
September 23rd, 2021 •
1,2, 3,4, 1,5
1Department of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 2Berta-Ottenstein-Programme for Clinician Scientists, Faculty of Medicine, University of Freiburg, 3Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, 4Department of Stereotactic and Functional Neurosurgery, Medical Center - University Freiburg, Faculty of Medicine, University of Freiburg, 5Center for Basics in Neuromodulation, Faculty of Medicine, University of Freiburg

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うつ病の慢性絶望マウスモデル(CDM)は、反復的な強制水泳セッションと、読み出しとしての別の遅延水泳段階からなる。これは、少なくとも4週間安定な慢性抑うつ様状態の誘導のための適切なモデルを表し、亜慢性および急性治療介入を評価するために修正可能である。

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ビヘイビア、第175号、
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