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Rekonstruere humant retinoblastom in vitro
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Reconstruct Human Retinoblastoma In Vitro
DOI:

06:52 min

October 11, 2022

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Chapters

  • 00:04Introduction
  • 00:46Generation of Human Retinoblastoma
  • 04:39Results: In Vitro Reconstruction of Human Retinoblastoma
  • 06:23Conclusion

Summary

Automatic Translation

Vi beskriver en metode til generering af humant retinoblastom (RB) ved at introducere bialleliske RB1-mutationer i humane embryonale stamceller (hESC). RB-cellelinjer kunne også med succes dyrkes ved hjælp af den isolerede RB i en skål.

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