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Optogenetisk fase overgang af TDP-43 i Spinal Motor Neuroner af Zebrafish Larver
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JoVE 신문 신경과학
Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae
DOI:

07:14 min

February 25, 2022

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Chapters

  • 00:04Introduction
  • 01:36Preparation of Light Emitting Diode (LED) for Blue Light Illumination
  • 02:13Imaging of Zebrafish Larvae Expressing Optogenetic TAR DNA-binding Protein 43 (TDP-43)
  • 03:58Light Stimulation of Optogenetic TDP-43h-Expressing Fish by Field Illumination of a Blue LED Light
  • 04:35Results: Characterization of TDP-43 Phase Transition in Spinal Motor Neurons of Zebrafish Larvae
  • 06:34Conclusion

Summary

자동 번역

Vi beskriver en protokol til at fremkalde fase overgang af TAR DNA-bindende protein 43 (TDP-43) af lys i spinal motor neuroner ved hjælp af zebrafisk som model.

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