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JoVE Journal Chemistry
Radiosyntese af 1-(2-[18F]Fluorethyle)-L-Tryptophan ved hjælp af en en-pot, to-trins protokol
 
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Radiosyntese af 1-(2-[18F]Fluorethyle)-L-Tryptophan ved hjælp af en en-pot, to-trins protokol

Article DOI: 10.3791/63025-v • 08:33 min • September 21st, 2021
September 21st, 2021 •
1,2, 1,2, 1,2, 2, 3, 1,2, 1,4
1Diagnostic & Research PET/MRI Center, Nemours/Alfred I. duPont Hospital for Children, 2Department of Radiology, Nemours/Alfred I. duPont Hospital for Children, 3Department of Neurology, Nemours/Alfred I. duPont Hospital for Children, 4Department of Biomedical Research, Nemours/Alfred I. duPont Hospital for Children

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Her beskriver vi radiosyntesen af 1-(2-[18F]Fluorethyle)-L-tryptophan, et positronemissionstomografibilleddannelsesmiddel til undersøgelse af tryptofanmetabolisme ved hjælp af en en-pot, to-trins strategi i et radiokemisk syntesesystem med gode radiokemiske udbytter, højt enantiomerisk overskud og høj pålidelighed.

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Kemi udgave 175 1-(2-[18F]Fluorethyl)-L-tryptophan radiosyntese tryptofanmetabolisme PET-billeddannelse kynureninvej
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