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导管内乙醇消融治疗在大鼠模型中预防乳腺癌的X射线可视化

JoVE 신문
암 연구학
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JoVE 신문 암 연구학

X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models

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导管内乙醇消融治疗在大鼠模型中预防乳腺癌的X射线可视化

DOI:

10.3791/64042-v

•

12:57 min

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December 09, 2022

•

Elizabeth Kenyon², Erin Zaluzec³, Katherine Powell², Maximilian Volk⁴, Shatadru Chakravarty⁵, Jeremy Hix⁶, Matti Kiupel, Erik M. Shapiro, Lorenzo F. Sempere²

¹Precision Health Program,Michigan State University, ²Department of Radiology,Michigan State University, ³Department of Pharmacology & Toxicology,Michigan State University, ⁴College of Osteopathic Medicine,Michigan State University, ⁵TechInsights Inc., ⁶IQ Advanced Molecular Imaging Facility,Michigan State University, ⁷Veterinary Diagnostic Laboratory, College of Veterinary Medicine,Michigan State University

Chapters

00:14Introduction
02:06Extended Anti-Inflammatory Treatment
02:57Preoperative Preparation
04:10Intraductal Injection
07:10Micro-CT Imaging
09:06Image Analysis
10:03Results
11:33Conclusion

Summary

자동 번역

描述了将化学烧蚀溶液输送到大鼠乳腺导管树以进行乳腺癌图像引导预防治疗的程序。通过直接插管到开口和导管内输注 70% 乙醇基消融液，可以靶向乳腺上皮细胞，从而以最小的侧支组织损伤。

Tags

X-Ray Visualization Intraductal Ethanol-Based Ablative Treatment Breast Cancer Prevention Rat Models Mammary Ductal Tree Ethyl Cellulose Carprofen Sucralose Gel Cups MicroCT Scans 3D Reconstructions

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