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血管紧张素II诱导的腹主动脉瘤小鼠模型中中心静脉导管的药物治疗及3D超声监测

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Drug Treatment by Central Venous Catheter in a Mouse Model of Angiotensin II Induced Abdominal Aortic Aneurysm and Monitoring by 3D Ultrasound

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血管紧张素II诱导的腹主动脉瘤小鼠模型中中心静脉导管的药物治疗及3D超声监测

DOI:

10.3791/64124-v

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10:09 min

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August 04, 2022

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Nahla Ibrahim, Johannes Klopf, Sonja Bleichert, Marc A. Bailey³, Albert Busch, Alexander Stiglbauer-Tscholakoff, Wolf Eilenberg, Christoph Neumayer, Christine Brostjan

¹Division of Vascular Surgery, Department of General Surgery,Medical University of Vienna and Vienna General Hospital, ²Leeds Institute for Cardiovascular and Metabolic Medicine, School of Medicine,University of Leeds, ³Leeds Vascular Institute,Leeds General Infirmary, ⁴Department for Visceral, Thoracic and Vascular Surgery,Technical University of Dresden and University Hospital Carl-Gustav Carus, ⁵Division of Cardiovascular and Interventional Radiology, Division of Molecular and Gender Imaging, Department of Biomedical Imaging and Image Guided Therapy,Medical University of Vienna and Vienna General Hospital

Chapters

00:04Introduction
00:55Pump Implantation
01:54Jugular Vein Catheterization
06:213D Ultrasound
08:08Results: Monitoring of Aneurysm Development by 3D Ultrasound
09:28Conclusion

Summary

자동 번역

该协议描述了在载脂蛋白E（ApoE）缺陷小鼠中通过血管紧张素II释放连续植入渗透泵以诱导腹主动脉瘤，以及使用颈静脉导管的血管通路端口进行重复药物治疗。尽管进行了背侧植入物，但通过 3D 超声可有效监测动脉瘤的发展。

Tags

Mouse Model Abdominal Aortic Aneurysm Drug Treatment Central Venous Catheter 3D Ultrasound Jugular Vein Catheterization APOE Deficient Anesthesia Surgical Procedure Vascular Access System Catheter Preparation Disinfection Blunt Dissection External Jugular Vein

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