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左冠状动脉结扎术：心肌梗死的外科小鼠模型
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Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction
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左冠状动脉结扎术：心肌梗死的外科小鼠模型

DOI:
10.3791/64387-v

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05:48 min

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August 09, 2022

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,
1Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, Department of Medicine,University of Pittsburgh, 2Department of Immunology,University of Pittsburgh, 3Department of Bioengineering, Swanson School of Engineering,University of Pittsburgh

Chapters

  • 00:05Introduction
  • 00:35Preparation and Endotracheal Intubation of the Mice
  • 02:23Permanent Ligation of the Left Coronary Artery
  • 03:51Post-Operative Care
  • 04:22Results: A Reproducible and Clinically Relevant Myocardial Infarction Murine Model to Improve the Left Coronary Artery Ligation
  • 05:19Conclusion

Summary

자동 번역

자동 번역

这里介绍的是小鼠左冠状动脉永久结扎的外科手术。该模型可用于研究心肌梗死后的病理生理学和相关炎症反应。

Tags

Left Coronary Artery LigationSurgical Murine ModelMyocardial InfarctionMouse ModelMIAnesthesiaBuprenorphineIntubationVentilatorThoracotomyLeft VentricleLeft Coronary Artery

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