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1Department of Anatomy, Cell Biology and Physiology,Indiana University School of Medicine, 2Department of Orthopaedic Surgery,Indiana University School of Medicine, 3Indiana Center for Musculoskeletal Health,Indiana University School of Medicine, 4School of Mechanical Engineering,Purdue University, 5Large Animal Resource Center,Indiana University School of Medicine, 6Department of Mechanical and Energy Engineering,Indiana University-Purdue University Indianapolis
Chapters
- 00:04Introduction
- 00:47Animal Preparation
- 01:49Surgical Exposure
- 03:36Impact of the Femoral Condyle
- 05:25Surgical Site Closure
- 06:23Results: Assessing Osteoarthritis Severity and Apoptotic Chondrocytes in the Impacted Medial Femoral Condyle
- 07:58Conclusion
Le modèle d’impact du condyle fémoral médial ouvert chez le lapin est fiable pour l’étude de l’arthrose post-traumatique (PTOA) et de nouvelles stratégies thérapeutiques pour atténuer la progression de la PTOA. Ce protocole génère un défaut cartilagineux isolé du condyle fémoral médial postérieur chez le lapin à l’aide d’une tour de chute basée sur un chariot avec une tête d’impacteur.
