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1Department of Anatomy, Cell Biology and Physiology,Indiana University School of Medicine, 2Department of Orthopaedic Surgery,Indiana University School of Medicine, 3Indiana Center for Musculoskeletal Health,Indiana University School of Medicine, 4School of Mechanical Engineering,Purdue University, 5Large Animal Resource Center,Indiana University School of Medicine, 6Department of Mechanical and Energy Engineering,Indiana University-Purdue University Indianapolis
Chapters
- 00:04Introduction
- 00:47Animal Preparation
- 01:49Surgical Exposure
- 03:36Impact of the Femoral Condyle
- 05:25Surgical Site Closure
- 06:23Results: Assessing Osteoarthritis Severity and Apoptotic Chondrocytes in the Impacted Medial Femoral Condyle
- 07:58Conclusion
Den öppna mediala lårbenskondylslagsmodellen hos kaniner är tillförlitlig för att studera posttraumatisk artros (PTOA) och nya terapeutiska strategier för att mildra PTOA-progression. Detta protokoll genererar en isolerad broskdefekt i den bakre mediala lårbenskondylen hos kaniner med hjälp av ett vagnsbaserat falltorn med ett slaghuvud.
