Journal
/
암 연구학
/
小鼠患者来源的癌细胞原位植入概括了晚期结直肠癌
JoVE 신문
암 연구학
Author Produced
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다.  전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
JoVE 신문 암 연구학
Orthotopic Implantation of Patient-Derived Cancer Cells in Mice Recapitulates Advanced Colorectal Cancer
Please note that all translations are automatically generated. Click here for the English version.

小鼠患者来源的癌细胞原位植入概括了晚期结直肠癌

DOI:
10.3791/64629-v

•

06:49 min

•

February 10, 2023

•

, , ,
1Stem Cells and Cancer Laboratory,Vall d’Hebron Institute of Oncology (VHIO), 2Preclinical Therapeutics Core,University of California San Francisco, 3CIBERONC

Chapters

  • 00:05Introduction
  • 00:54Derivation of Patient Cells
  • 03:37Orthotopic Injection in Cecum
  • 05:27Results: Histological Analysis of Orthotopic CRC-PDX Tumors and Therapeutic Efficacy of a Testing Drug
  • 06:26Conclusion

Summary

자동 번역

자동 번역

该方案描述了在免疫缺陷小鼠盲肠壁中将患者来源的癌细胞原位植入。该模型概括了晚期结直肠癌转移性疾病，并允许在肺和肝转移的临床相关情况下评估新的治疗药物。

Tags

Orthotopic ImplantationPatient-derived Cancer CellsColorectal CancerAdvanced Metastatic DiseaseMouse ModelCell DissociationCell SortingCell ResuspensionCecum Injection

Article

Embed

플레이리스트에 추가

Usage Statistics

Related Videos

肝大肠癌转移的高级动物模型：成像技术和转移性克隆性质

在直肠癌原位小鼠模型中循环肿瘤细胞的分离

病人衍生软组织肉瘤原代培养的建立

来自沙柯玛患者衍生异种移植物的肿瘤启动细胞的分离和表征

乳腺癌细胞原位注射到小鼠乳房脂肪板

患者衍生的人类泌尿细胞癌和结肠直肠癌肿瘤生长和自发转移的正交异种移植模型

建立胃癌患者衍生异种移植模型和原细胞系

毛尿胰腺腺腺腺癌超声引导正射植入

建立胰腺癌斑马鱼患者来源的异种移植物进行化学敏感性测试

多形性胶质母细胞瘤的转化原位模型

Read Article