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慢性肝纤维化小鼠模型用于研究胆道闭锁
JoVE 신문
면역학 및 감염병학
This content is Free Access.
JoVE 신문 면역학 및 감염병학
A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia
DOI:

09:12 min

February 03, 2023

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Chapters

  • 00:04Introduction
  • 00:50Establishment of the Chronic Fibrotic BA Mouse Model
  • 01:45Intraperitoneal Injection of the Mice
  • 02:36Collection of Sample Tissue
  • 03:13Fluorescein Angiography of the Extrahepatic Bile Duct
  • 03:41H&E Staining
  • 04:43CK19 and F4/80 Immunohistochemical Staining
  • 06:00Sirius Red Staining
  • 06:55Results: Effects of Anti‐Ly6G Antibody Treatment in a Mouse Model of Biliary Atresia (BA) Infected with RRV
  • 08:42Conclusion

Summary

자동 번역

我们建立了慢性肝纤维化小鼠模型,为病毒诱导的胆道闭锁(BA)肝纤维化机制研究提供了合适的动物模型,并为未来的BA治疗提供了平台。

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