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Flow Analysis of PDL1-Vaxx Antibody Blockade Using Magnetic Fluorescent Beads
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基于磁性荧光珠的PDL1-Vaxx肽疫苗诱导的PD-1/PD-L1相互作用抗体阻断的双报告流分析
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암 연구학
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JoVE 신문 암 연구학
Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction
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基于磁性荧光珠的PDL1-Vaxx肽疫苗诱导的PD-1/PD-L1相互作用抗体阻断的双报告流分析

Flow Analysis of PDL1-Vaxx Antibody Blockade Using Magnetic Fluorescent Beads

DOI:
10.3791/65467-v

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02:48 min

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July 07, 2023

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, ,
1Department of Obstetrics & Gynecology,The Ohio State University Wexner Medical Center, 2The James Comprehensive Cancer Center

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Keywords: Magnetic Fluorescent BeadsDual-reporter Flow AnalysisPDL1-Vaxx Peptide VaccinePD-1/PD-L1 InteractionAntibody BlockadeB-cell Epitope Peptide VaccinesImmune Checkpoint TargetsPD-L1 ProteinPD-1 LigandB-VaxxPD1-VaxxPDL1-VaxxCTLA4-VaxxCancer VaccinesHER2Immune Checkpoint MarkersCombination ImmunotherapiesTumor Growth InhibitionMetastasis PreventionPatient Survival

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