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1Institute for Biological Interfaces,Karlsruhe Research Centre, 2Institute for BioMedical Technology,University of Twente, 3Department of Materials Research,Institute for Heavy Ion Research, 4Institute of Microstructure Technology,Karlsruhe Research Centre, 5Institute for Micro Process Engineering,Karlsruhe Research Centre
Chapters
- 00:01Introduction
- 00:39Hot Embossing I: Moulding procedure
- 03:05Hot Embossing II: Trimming and milling
- 04:05Bonding of a microporous membrane to the back of the microcontainers
- 05:11SMART: Substrate Modification And Replication by Thermoforming
- 05:16SMART Technology I: Irradiation
- 06:19SMART Technology II: Microthermoforming
- 08:27SMART Technology III: Track Etching
We present two processes for the microfabrication of porous polymer chips for three-dimensional cell cultivation. The first one is hot embossing combined with a solvent vapour welding process. The second one uses a recently developed microthermoforming process combined with ion track technology leading to a significant simplification of manufacture.
Tags
MicrofabricationChip-sized ScaffoldsThree-dimensional Cell CultivationReproducible GeometryConstant QualityMicrofabrication TechnologiesManufacturingApplicationsCell ClustersDiffusion Path LengthNutrientsGasesApoptosisNecrosisInsufficient Nutrient And Gas SupplyCellular MetabolitesPolymer ChipCellChipMicrocontainersHot EmbossingMicro Injection MouldingMass ProductionPolymer Microstructures
