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Chapters
- 00:05Introduction
- 00:42Good-bye flat biology
- 02:31Spheroids
- 04:30Micro CellChips
- 06:50Latest generation of CellChips: Microthermoformed Containers
In the past many in vitro culture systems -- mainly monolayer cultures -- often suffered from the disadvantage that differentiated primary cells had a relatively short life-span and de-differentiated during culture. As a consequence, most of their organ-specific functions were lost rapidly. Thus, in order to reproduce better conditions for these cells in vitro, modifications and adaptations have been made to conventional monolayer cultures.
Tags
BioreactorsSurfaced-modified 3D-scaffoldsStem Cell ResearchIn Vitro Culture SystemsMonolayer CulturesDifferentiated Primary CellsOrgan-specific FunctionsModificationsAdaptationsCellChipsMicro-thermoformed ContainersSurface-patterningSignaling MoleculesSensorsSignal ElectrodesBasic ResearchCell BiologyToxicologyPharmacologyBiodegradable PolymersClinical ApplicationsMass Production
