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Adjunctive Exosome Therapy: Enhancing Myocardial Recovery Post-CABG Surgery

September 15th, 2023
1, 1, 2, 1, 1, 1, 3, 4,5, 1
1Department of Surgery, University of Minnesota, 2School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, 3Cardiology, Richmond VA Medical Center, 4Department of Research Service, Center for Veterans Research and Education, Veterans Affairs Health Care System, 5Department of Neuroscience, University of Minnesota

Summary
Automatic Translation

本研究提出了进行性冠状动脉狭窄导致的慢性心肌缺血的外科猪模型，导致心脏功能受损而无梗死。缺血后，动物接受非体外循环冠状动脉旁路移植术，心外膜放置干细胞来源的富含外泌体的胶原蛋白贴片。这种辅助治疗可改善心肌功能和恢复。

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