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Mouse Extended Hepatectomy Model for Liver Regeneration Studies

May 24th, 2024
1, 1, 1, 1, 1, 1,2
1Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Department of Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, 2The Transplant Institute and the Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School

Summary
Automatic Translation

Musemodellen med partiel 2/3 (66 %) hepatektomi er velbeskrevet i litteraturen, men mere udvidede hepatektomier, der efterligner small-for-size-syndrom efter levertransplantation, er sjældent blevet brugt. Vi beskriver en udvidet 78 % hepatektomiprocedure i en musemodel, der resulterer i ca. 50 % postoperativ dødelighed hos raske mus.

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