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Mouse Extended Hepatectomy Model for Liver Regeneration Studies

May 24th, 2024
1, 1, 1, 1, 1, 1,2
1Division of Vascular and Endovascular Surgery and the Center for Vascular Biology Research, Department of Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, 2The Transplant Institute and the Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School

Summary
Automatic Translation

Musmodellen av partiell 2/3 (66%) hepatektomi är väl beskriven i litteraturen, men mer utökade hepatektomier som efterliknar small-for-size-syndrom efter levertransplantation har sällan använts. Vi beskriver en utökad 78% hepatektomiprocedur i en musmodell som resulterar i cirka 50% postoperativ dödlighet hos friska möss.

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