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Physiologic Patient Derived 3D Spheroids for Anti-neoplastic Drug Screening to Target Cancer Stem Cells

Michael E. Bregenzer*¹, Ciara Davis*¹, Eric N. Horst*¹, Pooja Mehta*², Caymen M. Novak*¹, Shreya Raghavan*², Catherine S. Snyder*², Geeta Mehta^2,3,4

¹Department of Biomedical Engineering,University of Michigan, ²Department of Materials Science and Engineering,University of Michigan, ³Rogel Cancer Center, School of Medicine,University of Michigan, ⁴Macromolecular Science and Engineering,University of Michigan

Journal (Cancer Research)

Assessing Tumor Microenvironment of Metastasis Doorway-Mediated Vascular Permeability Associated with Cancer Cell Dissemination using Intravital Imaging and Fixed Tissue Analysis

George S. Karagiannis^2,3, Jessica M. Pastoriza^2,4, Lucia Borriello², Rojin Jafari², Anouchka Coste^2,4, John S. Condeelis^2,3,4, Maja H. Oktay^2,3,5, David Entenberg^2,3

¹Department of Anatomy and Structural Biology,Albert Einstein College of Medicine, ²Gruss-Lipper Biophotonics Center,Albert Einstein College of Medicine, ³Integrated Imaging Program,Albert Einstein College of Medicine, ⁴Department of Surgery,Montefiore Medical Center, ⁵Department of Pathology,Montefiore Medical Center

Journal (Cancer Research)

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib

Toshimitsu Yamaoka, Motoi Ohba, Yuki Matsunaga, Junji Tsurutani, Tohru Ohmori

¹Advanced Cancer Translational Research Institute,Showa University, ²Division of Breast Surgical Oncology, Department of Surgery,Showa University School of Medicine, ³Division of Allergology and Respiratory Medicine, Department of Medicine,Showa University School of Medicine

Journal (Cancer Research)

Rapid Generation of Primary Murine Melanocyte and Fibroblast Cultures

Brandon M. Murphy, Tirzah J. Weiss, Christin E. Burd²

¹Department of Cancer Biology and Genetics,The Ohio State University, ²Department of Molecular Genetics,The Ohio State University

Journal (Cancer Research)

Assessing Cell Viability and Death in 3D Spheroid Cultures of Cancer Cells

Michala G. Rolver, Line O. Elingaard-Larsen, Stine F. Pedersen

¹Section for Cell Biology and Physiology, Department of Biology, Faculty of Science,University of Copenhagen

Journal (Cancer Research)

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts

Dan Han, Veronica Rodriguez-Bravo, Sudeh Izadmehr, Josep Domingo-Domenech, Carlos Cordon-Cardo

¹Department of Pathology,Icahn School of Medicine at Mount Sinai

Journal (Cancer Research)

Extraction of Aqueous Metabolites from Cultured Adherent Cells for Metabolomic Analysis by Capillary Electrophoresis-Mass Spectrometry

Ami Maruyama², Kenjiro Kami, Kazunori Sasaki, Hajime Sato, Yuzo Sato², Katsuya Tsuchihara, Hideki Makinoshima^2,4

¹Shonai Regional Industry Promotion Center, ²Tsuruoka Metabolomics Laboratory,National Cancer Center, ³Human Metabolome Technologies, Inc, ⁴Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center,National Cancer Center

Journal (Cancer Research)

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Erin R. Bonner², Karim Saoud, Sulgi Lee², Eshini Panditharatna, Madhuri Kambhampati, Sabine Mueller⁵, Javad Nazarian^2,5

¹Center for Genetic Medicine,Children's National Health System, ²Institute for Biomedical Sciences,The George Washington University School of Medicine and Health Sciences, ³Dana-Farber Cancer Institute, ⁴Department of Neurology,University of California San Francisco, ⁵DIPG Centre of Expertise Zurich,Universitats-Kinderspital Zurich

Journal (Cancer Research)

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Hyeongsun Moon*¹, Leanne R. Donahue*¹, Dahihm Kim, Luye An, Andrew C. White

¹Department of Biomedical Sciences,Cornell University

Journal (Cancer Research)

Modeling Breast Cancer via an Intraductal Injection of Cre-expressing Adenovirus into the Mouse Mammary Gland

Dongxi Xiang², Luwei Tao², Zhe Li²

¹Division of Genetics, Department of Medicine,Brigham and Women's Hospital, ²Department of Medicine,Harvard Medical School

Journal (Cancer Research)

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Bayu Brahma, Rizky I. Putri, Lenny Sari, Ramadhan Karsono, Denni J. Purwanto, Walta Gautama, Bob Andinata, Samuel J Haryono

¹Department of Surgical Oncology,Dharmais Cancer Hospital, ²Department of Anatomical Pathology,Dharmais Cancer Hospital

Journal (Cancer Research)

Using Microarrays to Interrogate Microenvironmental Impact on Cellular Phenotypes in Cancer

Rebecca Smith, Kaylyn Devlin, David Kilburn, Sean Gross, Damir Sudar, Elmar Bucher, Michel Nederlof, Mark Dane, Joe W. Gray, Laura Heiser, James E. Korkola

¹Department of Biomedical Engineering, Knight Cancer Institute,Oregon Health and Science University, ²Quantitative Imaging Systems LLC

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