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Biologia
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Human In-Vivo Bioassay for the Tissue-Specific Measurement of Nociceptive and Inflammatory Mediators
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Biologia
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JoVE Journal Biologia
Human In-Vivo Bioassay for the Tissue-Specific Measurement of Nociceptive and Inflammatory Mediators

Human In-Vivo Bioassay for the Tissue-Specific Measurement of Nociceptive and Inflammatory Mediators

DOI:
10.3791/1074-v

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08:54 min

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December 01, 2008

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, , , ,
1Department of Anesthesia,Stanford University School of Medicine, 2Department of Anaesthesiology,University of Mannheim, 3Department of Anaesthesiology,University of Heidelberg

Capítulos

  • 00:00Título
  • 00:57Introduction
  • 01:40Inducing Artificial Sunburn and Preparation for Microdialysis
  • 03:47Catheter Placement
  • 06:13Sample Collection and Storage
  • 08:05Conclusion

Summary

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A technique is presented for the in-vivo collection of interstitial fluid samples from pertinent tissue sites (here, experimentally inflamed skin) for the measurement of biochemicals mediating pain and inflammation.

Tags

Human In-vivo BioassayNociceptive MediatorsInflammatory MediatorsMicrodialysis CathetersDermal DialysisExperimentally Inflamed SkinInterstitial FluidBiochemical-behavioral LinkBiomarkers Of Pain And InflammationPainful StimuliNew Drug CandidatesMultiplex Bead Array Immunoassays

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