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Orthotopic Aortic Transplantation: A Rat Model to Study the Development of Chronic Vasculopathy

JoVE Journal
Medicina

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JoVE Journal Medicina

Orthotopic Aortic Transplantation: A Rat Model to Study the Development of Chronic Vasculopathy

Orthotopic Aortic Transplantation: A Rat Model to Study the Development of Chronic Vasculopathy

DOI:

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08:32 min

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December 04, 2010

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Mandy Stubbendorff, Tobias Deuse², Anna Hammel, Robert C. Robbins, Hermann Reichenspurner, Sonja Schrepfer²

¹University Heart Center Hamburg, Transplant and Stem Cell Immunobiology Lab (TSI),University Hospital Hamburg, ²Stanford University School of Medicine

Capítulos

00:05Título
00:43Introduction
01:46Obtaining a Thoracic Aorta Graft From Donor
03:44Transplantation of Aortic Graft into Recipient
07:41Results of Orthotopic Aortic Transplantation
08:00Conclusion

Summary

Tadução automática

This video demonstrates the orthotopic aortic transplant model as a simple model to study the development of transplant vasculopathy (TVP) in rats.

Tags

Orthotopic Aortic Transplantation Rat Model Chronic Vasculopathy Transplant Vasculopathy Heterotopic Heart Transplant Model Laboratory Rodents Aortic Transplant Model Histological Evaluation PVG-to-ACI Model Cyclosporin A Treatment Acute Cellular Rejection Media Necrosis Xenogeneic Models

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