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A Necrotizing Enterocolitis Model for Mechanistic Studies and Drug Discovery

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Modèle microfluidique d’entérocolite nécrosante sur puce pour l’étude de la physiopathologie de la NEC

JoVE Journal
Medicina

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JoVE Journal Medicina

Microfluidic Necrotizing Enterocolitis-on-a-Chip Model for Studying NEC Pathophysiology

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Modèle microfluidique d’entérocolite nécrosante sur puce pour l’étude de la physiopathologie de la NEC

A Necrotizing Enterocolitis Model for Mechanistic Studies and Drug Discovery

DOI:

10.3791/200450-v

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06:10 min

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July 28, 2023

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Lauren C. Frazer, Yukihiro Yamaguchi, Corey M. Jania, Wyatt E. Lanik, Qingqing Gong, Dhirendra K. Singh, Stephen Mackay, Natalia S. Akopyants, Misty Good

¹Division of Neonatal-Perinatal Medicine, Department of Pediatrics,University of North Carolina at Chapel Hill, ²University of Nebraska College of Medicine, ³Department of Surgery,Washington University School of Medicine

Tags

Microfluidic Necrotizing Enterocolitis NEC Pathophysiology Chip Model Extracellular Matrix Epithelial Cells Endothelial Cells HIMEC Organoid Growth Media Chip Expansion Media

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