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Inducing Hyperlipidemia to Characterize Diastolic Dysfunction in HFpEF Mice

JoVE Journal
Medicina

This content is Free Access.

JoVE Journal Medicina

Inducing Hyperlipidemia to Characterize Diastolic Dysfunction in HFpEF Mice

Inducing Hyperlipidemia to Characterize Diastolic Dysfunction in HFpEF Mice

DOI:

10.3791/201537-v

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01:48 min

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March 29, 2024

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Monique Williams², Ali Kamiar³, Jose Manuel Condor Capcha², Monica Anne Rasmussen, Qusai Alitter, Rosemeire Kanashiro Takeuchi³, Lauro Mitsuru Takeuchi, Joshua M. Hare², Lina A. Shehadeh²

¹Department of Medicine, Division of Cardiology,University of Miami Leonard M. Miller School of Medicine, ²Interdisciplinary Stem Cell Institute,University of Miami Leonard M. Miller School of Medicine, ³Department of Molecular and Cellular Pharmacology,University of Miami Leonard M. Miller School of Medicine, ⁴Department of Medical Education,University of Miami Leonard M. Miller School of Medicine

Tags

Hyperlipidemia Heart Failure With Preserved Ejection Fraction (HFpEF)Murine Model Poloxamer-407 (P-407)Adeno-associated Virus 9-cardiac Troponin T-low-density Lipoprotein Receptor (AAV9-cTnT-LDLR)Diastolic Dysfunction Cardiac Ischemia Metabolic Syndrome Lipotoxicity

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