Journal
/
Medicina
/
Pseudofracture: An Acute Peripheral Tissue Trauma Model
JoVE Journal
Medicina
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Medicina
Pseudofracture: An Acute Peripheral Tissue Trauma Model

Pseudofracture: An Acute Peripheral Tissue Trauma Model

DOI:
10.3791/2074-v

•

10:08 min

•

April 18, 2011

•

, , , , ,
1Department of Surgery,University of Pittsburgh, 2Department of Orthopedic Surgery,University of Aachen Medical Center

Capítulos

  • 00:05Título
  • 00:49Introduction
  • 01:16Preparation of a Bone Solution
  • 06:05Surgical Procedure Pseudofracture Model = Soft Tissue Injury and Bone Solution Injection
  • 08:45Representative Results of Immune Responses Following Trauma
  • 09:49Conclusion

Summary

Tadução automática

Tadução automática

Pseudofracture, a reproducible murine model of sterile musculoskeletal trauma, allows for evaluation of late term post-traumatic immune responses. This article describes the procedural execution of the model step by step, including the potential for experimental model combinations to permit study of multiple trauma.

Tags

PseudofractureHyper-reactive Inflammatory ResponseMultiple Organ DysfunctionHigh MortalityDelayed ImmunosuppressionClinical ComplicationsInfectionMortalityImmunologic StudiesTransgenic MiceKnockout MiceIn Vivo ModelingMolecular PathwaysFracture Fixation TechniquesPseudofracture ModelExtremity Fracture EnvironmentDamaged Bone And Bone Marrow

Article

Embed

ADICIONAR À PLAYLIST

Usage Statistics

Vídeos Relacionados

Expired CO2 Measurement in Intubated or Spontaneously Breathing Patients from the Emergency Department

Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model

Using Quantitative Real-time PCR to Determine Donor Cell Engraftment in a Competitive Murine Bone Marrow Transplantation Model

Acute Brain Trauma in Mice Followed By Longitudinal Two-photon Imaging

Ischemic Tissue Injury in the Dorsal Skinfold Chamber of the Mouse: A Skin Flap Model to Investigate Acute Persistent Ischemia

Direct Mouse Trauma/Burn Model of Heterotopic Ossification

An Acute Retinal Model for Evaluating Blood Retinal Barrier Breach and Potential Drugs for Treatment

Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma

Isometric Contractility Measurement of the Mouse Mesenteric Artery Using Wire Myography

Read Article