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Large Scale Zebrafish-Based In vivo Small Molecule Screen
JoVE Journal
Biologia
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JoVE Journal Biologia
Large Scale Zebrafish-Based In vivo Small Molecule Screen
DOI:

07:03 min

December 30, 2010

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Capítulos

  • 00:05Título
  • 00:40Introduction
  • 01:02Zebrafish Egg Collection and 96-Well Plate Preparatin
  • 02:52Small Molecule Library
  • 04:23Screening for Effects of Small Molecules by Visual Inspection of Phenotypes
  • 05:51Small Molecule Detection with Zebrafish Chemical Screening Assay
  • 06:21Conclusion

Summary

Tadução automática

Zebrafish has emerged as a powerful in vivo platform for phenotype-based drug screens and chemical genetic analysis. Here, we demonstrate a simple, practical method for large-scale screening of small molecules using zebrafish embryos.

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