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Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive
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Biologia
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JoVE Journal Biologia
Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive

Population Replacement Strategies for Controlling Vector Populations and the Use of Wolbachia pipientis for Genetic Drive

DOI:
10.3791/225-v

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10:21 min

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July 04, 2007

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1Malaria Research Institute, Bloomberg School of Public Health,Johns Hopkins University

Capítulos

  • 00:00Introduction
  • 00:26Severity of Malaria Worldwide
  • 01:09Population Replacement Strategy
  • 02:19Gene Drive Systems
  • 03:15Challenges to Implementing a Gene Drive System
  • 03:53Wolbachia pipientis
  • 05:42Wolbachia Infections of Anopheles gambiae
  • 06:27Gene Drive Experiments in Controlled Settings
  • 07:22Ethical Considerations of Releasing Genetically Modified Mosquitoes
  • 08:21Obstacles to Population Replacement Strategies
  • 09:24Funding
  • 10:12End Credits

Summary

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In this interview, Jason Rasgon explains the concept of genetic drive and the characteristics of an effective gene drive system. The use of the endosymbiotic bacterium, Wolbachia pipientis, as a means to spread genes through mosquito populations, is hypothesized.

Tags

Population Replacement StrategiesControlling Vector PopulationsWolbachia PipientisGenetic DriveVector-borne DiseasesMalaria ControlDengue ControlSymbiotic BacteriaWolbachia Biology

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