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幸免神经损伤（SNI）模型引起的机械触感小鼠
JoVE Journal
Medicina
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JoVE Journal Medicina
The Spared Nerve Injury (SNI) Model of Induced Mechanical Allodynia in Mice
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幸免神经损伤（SNI）模型引起的机械触感小鼠

DOI:
10.3791/3092-v

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07:44 min

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August 18, 2011

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, , ,
1The Lundbeck Foundation Research Center MIND, Department of Biomedicine,Aarhus University, 2Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences,University of Copenhagen

Capítulos

  • 00:05Título
  • 01:56Collecting Baseline von Frey Measurements Prior to Surgery
  • 03:04Anesthesia and Preparation for Surgery
  • 04:14Surgery
  • 06:04Post-surgical Care and von Frey Measurements
  • 06:37Results: von Frey Testing of 8-10 Week-old Mice Before and After Surgery
  • 07:17Conclusion

Summary

Tadução automática

Tadução automática

幸免神经损伤的动物模型是描述以下的坐骨神经损毁的胫骨和腓总神经分支部分失神经支配的周围神经痛的小鼠模型，保持其余的腓肠神经不变。行为矫正机械触感量化冯弗雷细丝。

Tags

Spared Nerve Injury (SNI) ModelPeripheral Neuropathic PainChronic Pain ConditionTrauma To Sensory NervesPeripheral Nervous SystemMechanical AllodyniaTactile StimuliSNI Mouse ModelLigation Of Sciatic Nerve BranchesTibial NerveCommon Peroneal NerveSural NerveHypersensitivity In Lateral Area Of PawControl SideVon Frey FilamentsBending ForcePain ReactionPaw WithdrawalFlinchingPaw LickingPain Threshold

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