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基于计算机的蛋白质结构与功能预测议定书
JoVE Journal
Biologia
This content is Free Access.
JoVE Journal Biologia
A Protocol for Computer-Based Protein Structure and Function Prediction
DOI:

16:41 min

November 03, 2011

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Capítulos

  • 00:05Título
  • 02:21Running the I-TASSER Server
  • 03:37Structure Analysis
  • 05:58LOMETS Target Template Alignment
  • 07:30Structural Analogs in PDB and Enzyme Commission Number Prediction
  • 09:20Gene Ontology (GO) Term and Protein-ligand Bind site Predictions
  • 12:05Representative I-TASSER Results
  • 15:43Conclusion

Summary

Tadução automática

计算机准则的基础结构和功能的蛋白质使用的I - TASSER管道的特性描述。开始,从查询蛋白质序列生成三维模型使用多个线程的路线和迭代结构装配模拟。此后绘制功能的推论是基于匹配与已知的结构和功能的蛋白质。

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