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Murine Model of Allergen Induced Asthma
JoVE Journal
Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
Murine Model of Allergen Induced Asthma
DOI:

08:05 min

May 14, 2012

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Capítulos

  • 00:05Título
  • 01:10Allergen Sensitization and Intratracheal Challenge
  • 03:07Challenge by Nebulization
  • 03:43Determination of Hyperresponsiveness to Methacholine
  • 05:25Measurement of Cellular Infiltration into the Airspace
  • 07:12Differential Analysis of Airway Cells and Serum IgE Quantification in Control and Ovalbumin-treated Mice
  • 07:47Conclusion

Summary

Tadução automática

Experimental mouse models of allergic asthma offer new possibilities for studying disease pathogenesis and developing new therapeutics. These models are well suited to measuring factors governing the allergic immune response, airway inflammation, and pulmonary pathophysiology.

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