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Endothelialized Microfluidics voor het bestuderen van microvasculaire Interacties in Hematologische ziekten
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1Department of Pediatrics,Emory University School of Medicine, 2Wallace H. Coulter Department of Biomedical Engineering,Georgia Institute of Technology and Emory University, 3Aflac Cancer Center and Blood Disorders Service of Children’s Healthcare of Atlanta , 4Winship Cancer Institute of Emory University
Capítulos
- 00:05Título
- 01:11Fabrication of the Endothelial Microdevice
- 03:46Polydimethylsiloxane (PDMS) Preparation
- 06:25Seeding the Microfluidic Device with Endothelial Cells
- 08:49Endothelialized Microfluidics Reveal Abnormal Microvascular Interactions after Infusion with Blood from Patients with Hematologic Disease
- 10:35Conclusion
Een methode om cultuur een endotheelcel monolaag het gehele inwendige oppervlak van een 3D microfluïdische apparaat met microvasculaire grootte kanalen (<30 pm) beschreven. Deze<em> In vitro</em> Capillairen model kan de studie van biofysische interacties tussen bloedcellen, endotheelcellen en oplosbaar factoren hematologische aandoeningen.
Tags
MicrofluidicsEndothelialized MicrofluidicsMicrovascular InteractionsHematologic DiseasesMicrofabrication TechniquesBiological ExperimentsBiochemical ExperimentsMicro- And NanoscalesHematologic ProcessesBlood Cell DeformabilityBlood Cell AggregationMicrovascular Blood FlowBlood Cell-endothelial Cell InteractionsCultured Endothelial CellsMicrocirculationBiophysical Pathophysiology
