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Colorazione immunoistochimica di B7-H1 (PD-L1) in paraffina incorporate diapositive di tessuto pancreatico Adenocarcinoma
 
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Colorazione immunoistochimica di B7-H1 (PD-L1) in paraffina incorporate diapositive di tessuto pancreatico Adenocarcinoma

Article DOI: 10.3791/4059-v • 10:11 min • January 3rd, 2013
January 3rd, 2013 •
1,2, 1,2, 1,2,3, 1, 1,2,4, 3,5, 6, 1,2,5,7,8, 1,2,5,8, 1,2,4,5,7
1The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 2Department of Oncology, The Johns Hopkins University School of Medicine, 3Department of Dermatology, The Johns Hopkins University School of Medicine, 4Department of Surgery, Johns Hopkins University School of Medicine, 5The Sol Goldman Pancreatic Cancer Center, The Johns Hopkins University School of Medicine, 6Yale Cancer Center, Yale School of Medicine, 7The Skip Viragh Center for Pancreatic Cancer, The Johns Hopkins University School of Medicine, 8Department of Pathology, The Johns Hopkins University School of Medicine

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B7-H1 (PD-L1) e il suo legame al PD-1 forniscono una maggiore tumore segnale indotto immunosoppressiva nel microambiente del tumore. Una tecnica di colorazione immunoistochimica per caratterizzare l'espressione e la localizzazione di B7-H1 in adenocarcinoma pancreatico è descritto qui.

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Cancer Biology Numero 71 Medicina Immunologia Biochimica Biologia Molecolare Biologia Cellulare Chimica Oncologia immunoistochimica B7-H1 (PD-L1) l'adenocarcinoma del pancreas cancro al pancreas pancreas tumore cellule T immunità il cancro
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