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原位膀胱肿瘤模型和评价治疗膀胱萨纳
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Medicina
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JoVE Journal Medicina
An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
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原位膀胱肿瘤模型和评价治疗膀胱萨纳

DOI:
10.3791/4207-v

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08:43 min

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July 28, 2012

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, , , , ,
1Department of Urology and Helen Diller Comprehensive Cancer Center,University of California, San Francisco , 2Alnylam Pharmaceuticals, Inc.

Capítulos

  • 00:05Título
  • 00:23Intravesical Tumor Cell Injection
  • 04:00Bioluminescence Imaging
  • 04:45Ultrasound Imaging
  • 06:31Injection of saRNA
  • 07:45Conclusion

Summary

Tadução automática

Tadução automática

建立原位膀胱肿瘤模型来评估膀胱内交付萨纳和超声监测肿瘤的生长和发光成像的抗肿瘤作用。

Tags

Orthotopic Bladder Tumor ModelIntravesical SaRNA TreatmentBladder Cancer TreatmentSmall Activating RNAOrthotopic Xenograft Mouse ModelUrethral CatheterizationInhaled General AnestheticChemical BurnIntravesical Silver Nitrate SolutionBladder Glycosaminoglycan LayerHuman Bladder Cancer CellsKU-7-luc2-GFP CellsCatheterIn Vivo Bladder UltrasoundBioluminescent ImagingLipid Nanoparticles (LNPs)Tumor Growth Monitoring

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