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Manufacturing and Using Piggy-back Multibarrel Electrodes for In vivo Pharmacological Manipulations of Neural Responses
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Capítulos
- 00:05Título
- 01:13Pull Glass Electrodes
- 02:57Assemble Piggy-back Electrode
- 04:06Fill and Prepare Electrodes
- 04:41Results: Titration of Ejection Currents
- 06:15Conclusion
Iontophoresis of neural agonists and antagonists during extracellular in vivo recordings is a powerful way to manipulate a neuron’s microenvironment. These manipulations can most easily be done via piggy-back multibarrel electrodes. Here we describe how to manufacture them and use them during auditory recordings.
Tags
Piggy-back Multibarrel ElectrodesIn Vivo Pharmacological ManipulationsNeural ResponsesSingle Neuron RecordingsFiring PropertiesExcitatory InputsInhibitory InputsInformation ProcessingNeural SystemsFunctional Role Of InputsDynamically Suppress InputsReversibly Eliminate InputsNeuron’s Output ChangesPiggy-back Multibarrel ElectrodesSingle Barrel Recording ElectrodeMultibarrel Drug ElectrodeSynaptic AgonistsSynaptic AntagonistsIontophoretic Application Of Pharmacological Agents
