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光化学缺血：一种微创和可重复性的光化学皮质病变模型小鼠中风研究

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Medicina
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JoVE Journal Medicina

Photothrombotic Ischemia: A Minimally Invasive and Reproducible Photochemical Cortical Lesion Model for Mouse Stroke Studies

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光化学缺血：一种微创和可重复性的光化学皮质病变模型小鼠中风研究

DOI:

10.3791/50370-v

•

08:40 min

•

June 09, 2013

•

Vivien Labat-gest^2,3, Simone Tomasi^3,4

¹Department of Neuroscience,University of Turin , ²Neuroscience Institute of Turin (NIT),University of Turin , ³Neuroscience Institute Cavalieri-Ottolenghi (NICO),University of Turin , ⁴Department of Anatomy, Pharmacology and Forensic Medicine,University of Turin

Capítulos

00:01Título
01:09Introduction
01:54Preparation
02:30Tool presentation
03:12Anesthesia procedure
04:05Surgery for illumination of the targeted area
05:44Rose Bengal injection and activation
06:20Suture
07:06Representative results
07:55Conclusion

Summary

Tadução automática

的Photothrombosis是一种快速，微创技术领域的兴趣，高度可重复的方式诱导小以及分隔梗死。它特别适用于为研究细胞和分子在转基因小鼠中脑的可塑性响应相关。

Tags

Photothrombotic Ischemia Photochemical Cortical Lesion Mouse Stroke Model Rose Bengal Endothelial Damage Platelet Activation Thrombosis Non-invasive Reproducible Transgenic Mice Brain Plasticity

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