/
/
Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
É necessária uma assinatura da JoVE para visualizar este conteúdo. Faça login ou comece sua avaliação gratuita.
Capítulos
- 00:05Título
- 01:44Catalyst Patterning and Chemical Vapor Deposition Growth for Single-walled Carbon Nanotubes
- 03:14SWNT Field-effect Transistor Fabrication
- 04:28Chemical Functionalization of Carbon Nanotube Sidewalls
- 05:11Preparation of Polydimethylsiloxane Mold for Fluid Chamber
- 06:12Preparation of Microfluidic Flow Channel
- 07:43AC Electrical Measurement Setup
- 08:58Electrical Measurements in Solution: No Flow and Real Time Flow
- 10:00Results: Functionalized SWNT FETs for High-Frequency Sensing of Biomolecules in High Ionic Strength Solutions
- 11:55Conclusion
We describe the device fabrication and measurement protocol for carbon nanotube based high frequency biosensors. The high frequency sensing technique mitigates the fundamental ionic (Debye) screening effect and allows nanotube biosensor to be operated in high ionic strength solutions where conventional electronic biosensors fail. Our technology provides a unique platform for point-of-care (POC) electronic biosensors operating in physiologically relevant conditions.
