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肾小囊和异种移植皮下颗粒植入前列腺癌发生和良性前列腺增生症的评价
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JoVE Journal Medicina
Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
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肾小囊和异种移植皮下颗粒植入前列腺癌发生和良性前列腺增生症的评价

DOI:
10.3791/50574-v

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08:38 min

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August 28, 2013

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, , , , ,
1Department of Urology,University of Wisconsin-Madison, 2Medical Scientist (MD/PhD) Training Program,University of Rochester School of Medicine & Dentistry, 3Molecular and Environmental Toxicology Center,University of Wisconsin-Madison

Capítulos

  • 00:05Título
  • 01:44Preparation of Compressed Hormone Pellet
  • 02:57Preparation of Fire Polished Glass Pipette
  • 03:27Renal Capsule Xenografting
  • 06:02Subcutaneous Pellet Implantation
  • 06:35Results: Renal Capsule Grafting
  • 07:17Conclusion

Summary

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我们描述了压缩激素粒料的制造方法，以及皮下外科手术植入到小鼠体内。这种策略可以与细胞和组织异种移植物下的无胸腺裸小鼠的肾被膜，以评估内分泌癌和良性前列腺生长的调节生长相结合。

Tags

Prostate CarcinogenesisBenign Prostatic HyperplasiaSex Steroid HormonesAndrogenEstrogenSubcutaneous Pellet ImplantationRenal Capsule XenograftingHormone RegulationProstate Cell RecombinantsImmunocompromised Mice

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