Journal
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複屈折およびタッチ呼び起こすエスケープ応答アッセイによる幼虫のゼブラフィッシュ骨格筋の欠陥の分析
JoVE Journal
Biologia
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JoVE Journal Biologia
Analysis of Skeletal Muscle Defects in Larval Zebrafish by Birefringence and Touch-evoke Escape Response Assays
DOI:

08:01 min

December 13, 2013

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Capítulos

  • 00:05Título
  • 01:44In vivo Analysis of Skeletal Muscle Structure by Birefringence
  • 04:23Touch-evoked Escape Behavior Assay
  • 05:10Results: Representative WT and Mutant Skeletal Muscle Analyses
  • 07:28Conclusion

Summary

Tadução automática

The zebrafish is now an established and powerful tool for modeling muscular dystrophies, congenital myopathies, and related neuromuscular diseases. Birefringence and touch-evoked escape behavior are two common noninvasive assays used to determine the degree of muscular disorganization and locomotive impairment of zebrafish embryos during early development.

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