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Intramyocardial Cell Delivery: Observations in Murine Hearts
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JoVE Journal Medicina
Intramyocardial Cell Delivery: Observations in Murine Hearts

Intramyocardial Cell Delivery: Observations in Murine Hearts

DOI:
10.3791/51064-v

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08:12 min

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January 24, 2014

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, , ,
1Magdi Yacoub Institute,Imperial College London, 2National Heart and Lung Institute,Imperial College London, 3Australian Regenerative Medicine Institute,Monash University

Capítulos

  • 00:05Título
  • 01:19Presurgical Preparation
  • 02:57Surgical Procedure
  • 06:13Results: Cell Detection and Analysis After Injection
  • 07:49Conclusion

Summary

Tadução automática

Tadução automática

Intramyocardial cell delivery in murine models of cardiovascular diseases, such as hypertension or myocardial infarction, is widely used to test the therapeutic potential of different cell types in regenerative studies. Therefore, a detailed description and a clear visualization of this surgical procedure will help to define the limits and advantages of cardiovascular cell therapeutic analyses in small rodents.

Tags

Keywords: Intramyocardial Cell DeliveryCell TherapyCardiac Stem CellsMesenchymal Stem CellsCardiospheresMyocardial InjectionMicrosurgical ProcedureHistological AnalysisImmunocompromised Mice

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