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神经干/祖细胞在小鼠EAE的慢性全身性注射

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Imunologia e Infecção

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JoVE Journal Imunologia e Infecção

Systemic Injection of Neural Stem/Progenitor Cells in Mice with Chronic EAE

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神经干/祖细胞在小鼠EAE的慢性全身性注射

DOI:

10.3791/51154-v

•

09:24 min

•

April 15, 2014

•

Matteo Donegà, Elena Giusto, Chiara Cossetti, Julia Schaeffer, Stefano Pluchino²

¹Department of Clinical Neurosciences, John Van Geest Centre for Brain Repair,University of Cambridge, UK, ²NIHR Biomedical Research Center,University of Cambridge, UK

Capítulos

00:05Título
02:00Neural Stem/Progenitor Cells (NPCs) Isolation and Infection
04:34Injection of Neural/Progenitor Cells into the Tail Vein
06:57Results: NPC Isolation and GFP Expression
08:29Conclusion

Summary

Tadução automática

神经干/祖细胞（的NPC）的移植持有再生神经内科伟大的应许。全身交付的NPC已经变成有效的，低侵入性的，而且治疗非常有效的协议，提供干细胞在大脑和受中枢神经系统的实验性慢性炎症性损害啮齿类动物和灵长类动物的脊髓。

Tags

Neural Stem/progenitor Cells NPC Transplantation Systemic Delivery Intravenous Injection Intracerebroventricular Injection Experimental Autoimmune Encephalomyelitis EAE Chronic CNS Inflammatory Demyelination Brain Repair Regenerative Neurology

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