Journal
/
Imunologia e Infecção
/
Myelin oligodendrocyt Glycoprotein (MOG<sub> 35-55</sub>) Induceret eksperimentel autoimmun encephalomyelitis (EAE) i C57BL / 6 mus
JoVE Journal
Imunologia e Infecção
This content is Free Access.
JoVE Journal Imunologia e Infecção
Myelin Oligodendrocyte Glycoprotein (MOG35-55) Induced Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6 Mice

Myelin oligodendrocyt Glycoprotein (MOG<sub> 35-55</sub>) Induceret eksperimentel autoimmun encephalomyelitis (EAE) i C57BL / 6 mus

DOI:
10.3791/51275-v

•

08:03 min

•

April 15, 2014

•

, , ,
1Department of Neurology,University of Münster, 2Interdisciplinary Center for Clinical Research (IZKF), Münster, 3Institute of Physiology – Neuropathophysiology,University of Münster

Capítulos

  • 00:05Título
  • 01:51Preparation of MOG35-55 Emulsion
  • 04:19Preparation of Pertussis Toxin
  • 05:03Animal Immunization
  • 06:14EAE Monitoring
  • 07:04Results: EAE Symptoms After Immunization
  • 07:29Conclusion

Summary

Tadução automática

Tadução automática

Eksperimentel autoimmun encephalomyelitis (EAE) er en etableret dyremodel for multipel sklerose. C57BL / 6 mus immuniseres med myelin oligodendrocyt glycoprotein (MOG)-peptid 35-55 (MOG 35-55), hvilket resulterer i en stigende paralyse forårsaget af autoreaktive immunceller i det centrale nervesystem. Protokoller for sygdom induktion og overvågning vil blive diskuteret.

Tags

Keywords: Experimental Autoimmune EncephalomyelitisEAEMultiple SclerosisMOG35-55C57BL/6 MiceNeuroinflammationDemyelinationAutoimmunityAnimal Model

Article

Embed

ADICIONAR À PLAYLIST

Usage Statistics

Vídeos Relacionados

check_url/pt/51275?article_type=v

Induction of Experimental Autoimmune Hypophysitis in SJL Mice
check_url/pt/51275?article_type=v

Overvinde unresponsiveness i eksperimentel autoimmun encephalomyelitis (EAE) Resistente musestammer ved adoptiv overførsel og antigenudfordring
check_url/pt/51275?article_type=v

Induktion af Experimental Autoimmune Encephalomyelitis i mus og evaluering af sygdommen-afhængige Fordeling af immunceller i forskellige væv
check_url/pt/51275?article_type=v

Enkel og effektiv produktion og oprensning af Mouse Myelin oligodendrocyt Glycoprotein for Eksperimentel Autoimmune Encephalomyelitis Studies
check_url/pt/51275?article_type=v

Visualisere værdiforringelse af endotel og Glial barrierer af neurovaskulære enhed under eksperimentelle Autoimmune Encephalomyelitis In Vivo
check_url/pt/51275?article_type=v

Adoptivimmunterapi af iNKT-celler i glucose-6-fosfatisomerase (G6PI)-Induceret RA-mus
check_url/pt/51275?article_type=v

Flow cytometrisk analyse af lymfocyt infiltration i centralnervesystemet under eksperimentel autoimmun encephalomyelitis
check_url/pt/51275?article_type=v

Adjuverende aktivitet af Mycobacterium paratuberculosis til forbedring af immunogeniciteten af autoantigener under eksperimentel autoimmun encephalomyelitis
check_url/pt/51275?article_type=v

Scoring Centralnervesystemet betændelse, demyelinisering, og axon skade i eksperimentel autoimmun encephalomyelitis
check_url/pt/51275?article_type=v

Quantification of Autoreactive Antibodies in Mice upon Experimental Autoimmune Encephalomyelitis

Read Article