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测量脊髓突触前抑制小鼠背根电位记录<em>在体内</em

JoVE Journal
Neurociência

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JoVE Journal Neurociência

Measuring Spinal Presynaptic Inhibition in Mice By Dorsal Root Potential Recording In Vivo

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测量脊髓突触前抑制小鼠背根电位记录<em>在体内</em

DOI:

10.3791/51473-v

•

09:48 min

•

March 29, 2014

•

Benedikt Grünewald², Christian Geis²

¹Hans Berger Department of Neurology,Jena University Hospital, Jena, Germany, ²Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC),Jena University Hospital, Jena, Germany

Capítulos

00:00Title/Introduction
02:23Preparations for Experiment
03:19Animal Preparation for Recording Procedure
06:00Separating Dorsal Roots and Electrode Positioning
07:35Example Data
08:35Conclusion

Summary

Tadução automática

GABA能突触前抑制是在脊髓电机和脊髓网络感官信号集成的重要功能强大的抑制机制。底层的初级传入去极化可以通过记录背根电位（DRP）来测量。在这里，我们证明在体内录音DRP小鼠的方法。

Tags

Keywords: Presynaptic Inhibition Dorsal Root Potential Primary Afferent Depolarization GABAergic Spinal Cord In Vivo Mice Pain Motor Hyperexcitability Suction Electrode Transgenic Mouse Models Spinal Pathophysiology

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