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阵列比较基因组杂交（CGH阵列），用于检测基因拷贝数变异的

JoVE Journal
Biologia

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JoVE Journal Biologia

Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants

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阵列比较基因组杂交（CGH阵列），用于检测基因拷贝数变异的

DOI:

10.3791/51718-v

•

09:16 min

•

February 21, 2015

•

Joo Wook Ahn, Michael Coldwell, Susan Bint, Caroline Mackie Ogilvie

¹Cytogenetics Department,Guy’s & St Thomas’ NHS Foundation Trust, ²Cytogenetics Department,Viapath Analytics

Capítulos

00:05Título
01:13Labeling Reaction and Purification of DNA
03:47Hybridization
06:30Washing and Scanning Slides
08:50Conclusion

Summary

Tadução automática

阵列CGH为基因拷贝数变异的检测已经取代G-带状核型分析。本文介绍了技术及其在诊断服务实验室的应用。

Tags

Keywords: Array CGH Genomic Copy Number Variants DNA Labeling Fluorochromes Hybridization Oligonucleotide Probes Probe Density Clinical Diagnostic Service Genome Analysis Copy Number Detection

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