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Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States
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JoVE Journal Medicina
Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States

DOI:
10.3791/52019-v

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07:09 min

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April 01, 2015

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, , ,
1Wallace H. Coulter Department of Biomedical Engineering,Georgia Institute of Technology & Emory University School of Medicine, 2Parker H. Petit Institute for Bioengineering & Bioscience,Georgia Institute of Technology, 3George W. Woodruff School of Mechanical Engineering,Georgia Institute of Technology

Capítulos

  • 00:05Título
  • 01:14Confocal Microscopy Evaluation of Glycated Clot Structures
  • 02:50Confocal Microscopy Evaluation of Fibrin Clots Containing Red Blood Cells (RBCs) from Sickle Cell Patients
  • 04:06Confocal Microscopy Evaluation of Fibrinolysis Rates in Glycated Clot Structures
  • 05:19Results: Confocal Microscopy Analysis of Glycated Fibrin Clot Structures
  • 06:38Conclusion

Summary

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In this manuscript, experimental techniques, including blood preparation, confocal microscopy, and lysis rate analysis, to examine the morphological differences between normal and abnormal clot structures due to diseased states are presented.

Tags

Keywords: Fibrin ClotClot StructureClot MorphologyConfocal MicroscopyClot LysisDiabetesSickle Cell AnemiaThrombosisExperimental TechniquesImaging

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