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쥐 심근 경색을 유도 최소 침습 수술
JoVE Journal
Medicina
This content is Free Access.
JoVE Journal Medicina
Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice
DOI:

09:05 min

May 04, 2015

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Capítulos

  • 00:05Título
  • 01:19Intubation
  • 02:34Myocardial Infarction Induction
  • 04:13Suture and Recovery
  • 04:57Myocardial Infarction Analysis
  • 06:50Results: Representative Myocardial Infarction Analyses
  • 08:29Conclusion

Summary

Tadução automática

A highly reproducible model for myocardial infarction in mice with minimal invasive manipulations is described. The model can be easily performed, resulting in a high reproducibility and survival rate. Thus, the described model will reduce the number of required animals as requested by the 3R principle (Replacement, Refinement and Reduction).

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