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単離と異なる高齢マウス胸腺移植片の移植。
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Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
Isolation and Transplantation of Different Aged Murine Thymic Grafts.
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単離と異なる高齢マウス胸腺移植片の移植。

DOI:
10.3791/52709-v

•

05:47 min

•

May 13, 2015

•

, , ,
1Department of Microbiology and Immunology,University of North Carolina at Chapel Hill

Capítulos

  • 00:05Título
  • 01:00Newborn and Adult Thymus Preparation
  • 02:20Thymus Implantation Under the Kidney Capsule
  • 04:32Results: Successful Engraftment of Donor Thymic T Cells
  • 05:25Conclusion

Summary

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Tadução automática

This report provides a detailed description of transplanting murine thymi from different aged donor mice under the kidney capsule of immunodeficient mouse recipients. The goal of this approach is to model T cell development and thymic selection events in vivo.

Tags

Thymic GraftThymic SelectionThymic TransplantationThymic FunctionT Cell DevelopmentImmune ReconstitutionScid RecipientAge-dependent Thymic Events

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