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Användning av ultrahög Field MRI i Small Gnagare Modeller av polycystisk njursjukdom för<em> In Vivo</em> Fenotypning och narkotikamissbruk
JoVE Journal
Medicina
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JoVE Journal Medicina
Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
DOI:

07:35 min

June 23, 2015

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Capítulos

  • 00:05Título
  • 01:40Scanner Configuration and Animal Preparation
  • 02:56MRI Experiment
  • 05:24Results: Structural Changes in a Mouse Model of Polycystic Kidney Disease Shown with Ultra-high Field MRI
  • 06:51Conclusion

Summary

Tadução automática

The use of ultra-high field MRI as a non-invasive way to obtain phenotypic information of rodent models for polycystic kidney disease and to monitor interventions is described. Compared with the traditional histological approach, MRI images can be acquired in vivo, allowing for longitudinal follow-up.

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